CUSTOM ANTIBODY SOLUTIONS

Looking for a partner who can design the exact antibody you need, not force you into a standard package?

At CER Groupe, we believe that antibody discovery should start with your target and your application, not with a predefined catalogue of immunization packages. With more than 25 years of expertise, an ISO9001‑certified platform, and an in‑house animal facility hosting 12 species including llamas, we work side‑by‑side with you to design the most efficient route to the antibody you require.

Whether you are developing a diagnostic assay, a biotherapeutic research tool, or a novel biosolution for agrifood, our teams help define the optimal strategy: species, immunization approach, screening technologies, formats, engineering options and production readiness.

Why Choose CER Groupe?

A partner that adapts to your target, not the opposite

Instead of imposing a predetermined workflow, we build a custom design plan with you, starting from your target and intended application. This includes antigen design support, species selection, screening depth and format choice.

Integrated infrastructure

  • ISO9001-certified facility since 1995
  • 12,500 m² in‑house animal facility with rabbits, rodents, llamas, goats, sheep, pigs, cows, chickens, rodents and llamas
  • Full biosecurity, 3R compliance and controlled timelines
  • Access to advanced screening platforms and antibody engineering capabilities
  • Commercial‑scale manufacturing for diagnostic applications (via dedicated biomanufacturing pages)
  • Integrated preclinical capabilities for biotech (imaging, biodistribution, in vivo PoC)

Proven track record

  • 100,000+ antibody programs completed
  • Experience covering diagnostics, biotech R&D, agrifood biosolutions and immunotherapy research
  • Scientific and administrative support at every stage

Our Custom Antibody Portfolio

Polyclonal Antibodies

Share your target and intended application, we define the most appropriate species, immunization strategy and purification route to deliver the polyclonal antibody profile you need.

  • Fast 28‑day rabbit programs
  • Species: rabbit, goat, sheep, pig, cow, chicken, rodents
  • Large‑scale production (kg‑scale pAb)
  • Hapten, peptide, protein and up to BSL-2 agents immunizations
  • DNA immunization available as an optional strategy
  • Immunoaffinity and antigen-specific purification capacity
  • Guaranteed titer options
  • Freeze‑drying / lyophilisation
  • Application validation (ELISA, Western Blot, flow cytometry, IF, sandwich assays)
Monoclonal Antibodies

We design the monoclonal workflow that best fits your analytical or diagnostic requirements, choosing between hybridoma, single‑cell technologies or recombinant discovery formats.

  • Mouse, rat and rabbit mAbs
  • Hybridoma & single B‑cell screening
  • FACS‑based fast cloning
  • Optional DNA immunization
  • Physico‑chemical & biofunctional characterization
  • Chimerization, reformatting, conjugation
  • Secured cryostorage
  • Recombinant production including:
  • Roller bottles and CL1000 systems
  • Transient expression HEKsPer‑T(>100 mg/L)Batch‑to‑batch reproducibility for diagnostics
VHH / sdAb / Nanobody Discovery

Tell us your target and application, and we define the best immunization and screening strategy to generate high‑performing VHH candidates—from llama immunization to recombinant expression.

  • In‑house llama immunization
  • Phage display
  • Functional screening by
  • Microfluidic droplet B‑cell sequencing (technology in development — open to collaborations)
  • Reformatting (VHH‑Fc, bispecifics, fusion formats)
  • Expression in HEKsPer‑T or microbial systems
  • Ideal for diagnostics, biotech research tools and agrifood biosolutions
Anti‑Idiotype Antibodies

We help determine the most relevant anti‑idiotype format for your bioanalytical strategy—blocking, non‑blocking or complex‑specific.

  • For ADA, PK and immunogenicity assessment
  • pAb, mAb or recombinant strategies
  • F(ab’)₂ digestion workflows for rapid timelines ; Fab/scFv recombinant expression
  • Tailored purification strategies
  • Application support (bridging ELISA, competition assays)

Antibody Engineering

Starting from your clone or sequence, we define the optimal reformatting, screening or engineering approach to meet your functional objectives.

  • VH/VL sequencing or de novo sequencing
  • Recombinant production
  • Reformatting: scFv, Fab, chimeras, IgG (bacterial/mammalian cells)
  • Computational biology-assisted variant generation (affinity, stability, solubility modulation)
  • Reporter cell line generation
  • Developability assessment

Antibody Side Services

We can support specific steps of your workflow, from purification to conjugation or characterization, depending on where you are in your project.

  • Fragmentation
  • Conjugation
  • Immuno-affinity purification column preparation
  • Freeze‑drying
  • Characterization (including intact mass, N‑glycan, peptide mapping, affinity, potency)
  • Antibody pairing
  • Application validation
  • Preclinical development models

Workflow : From Concept to Delivery

Once we know your target and intended application, we co‑create a personalised antibody development route with clear milestones and deliverables.

1. Project Design

Antigen design, species choice, immunogenicity strategy, optional conjugation, optional DNA immunization.

2. Immunization

Classical, long‑term or fast‑track protocols (including 28‑day rabbit).

3. Screening & Selection

Hybridoma, ELISA, flow cytometry, functional assays, B‑cell sorting, phage display.

4. Purification & Characterization

Protein A/G, antigen-affinity, SEC, functional and physicochemical testing.

5. Engineering & Recombinant Production

Reformatting, sequence work, HEKsPer‑T expression.

6. Deliverables

Purified antibodies, CoA, project report, optional secured cryostorage.

Quality & Compliance

  • ISO9001 certified
  • 3R‑compliant animal facility
  • Biosecurity and traceability
  • Full confidentiality & IP protection
  • Transparent documentation

Key Figures (placeholders)

  • 25+ years of experience
  • 100,000+ antibody programs
  • 12 species including llamas
  • 12,500 m² animal facility
  • Multi‑gram recombinant capacity – Kg polyclonal capacity